Past Issue

Volume 15, Number 4, Winter 2014, Serial Number: 60, Pages: 274-281

Potential Uses for Cord Blood Mesenchymal Stem Cells


Morteza Zarrabi, M.D, 1, Seyed Hadi Mousavi, Ph.D, 2, Saeid Abroun, Ph.D, 2, *, Bahareh Sadeghi, M.Sc, 1,
Royan Stem Cell Technology, Cord Blood Bank, Tehran, Iran
Department of Hematology, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran
* Corresponding Address: P.O.Box 14155-111 Department of Hematology School of Medical Sciences Tarbiat Modares University TehranIran EmailAbroun@modares.ac.ir

Abstract

Stem cell therapy is a powerful technique for the treatment of a number of diseases. Stem cells are derived from different tissue sources, the most important of which are the bone marrow (BM), umbilical cord (UC) blood and liver. Human UC mesenchymal stem cells (hUC-MSCs) are multipotent, non-hematopoietic stem cells that have the ability to self-renew and differentiate into other cells and tissues such as osteoblasts, adipocytes and chondroblasts. In a number of reports, human and mouse models of disease have hUC-MSCs treatments. In this article, we review studies that pertain to the use of hUC-MSCs as treatment for diseases.