Past Issue

Volume 12, Supplement 1,Winter 2011 (Presented at The 1st International Student Congress) Pages: 24-24

O-13: Expression of P53 and P63 in Epithelium of Dentigerous cyst and Odontogenic Keratocyst


P53 and P63 are tumor suppressor genes and their mutations are known to cause changes in normal function of cells. Dentigerous cyst is the most common odontogenic cyst , and odontogenic keratocyst (Keratocystic Odontogenic Tumor = KOT) has a different mechanism of growth and different biological behaviors from other odontogenic cysts.In this study expression of P53 and P63 genes in epithelium of dentigerous Cysts and odontogenic Keratocyst were evaluated . This approach can can be used as an early diagnostic method and approach in treatment in the management of these cysts