O-13: Expression of P53 and P63 in Epithelium of Dentigerous cyst and Odontogenic Keratocyst


Dehnad V *, Yassaee V , Mashhadi Abbas F , Bandehpour M ,

0

P53 and P63 are tumor suppressor genes and their mutations are known to cause changes in normal function of cells. Dentigerous cyst is the most common odontogenic cyst , and odontogenic keratocyst (Keratocystic Odontogenic Tumor = KOT) has a different mechanism of growth and different biological behaviors from other odontogenic cysts.In this study expression of P53 and P63 genes in epithelium of dentigerous Cysts and odontogenic Keratocyst were evaluated . This approach can can be used as an early diagnostic method and approach in treatment in the management of these cysts