O-17: Recombinant Adenovirus Expressing Overlapping Region of NS3 Gene: New Candidate for HCV Molecular Therapy


Hosseini S Y *, Sabahi F , Modarressi MH , Moazzeni , Saberi-Firoozi M , Ravanshad M , Mojarrad M ,

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So far developing a safe and effective vaccine for resolving Hepatitis C virus infection remain a big challenge but improving subject. Adenoviral vectors containing HCV genes become one of the best Abstract of the 1st Int. Student Congress on Cell & Molecular Medicine Cell Journal(Yakhteh), Vol 12, Suppl 1, Winter 2011 26 vaccine candidates for induction of anti-HCV cellular immunity. In this project, our aim was to prepare a recombinant adenoviral vector containing an overlapping region covering both helicase and protease sequences of NS3 gene from HCV