Past Issue

Volume 12, Supplement 1,Winter 2011 (Presented at The 1st International Student Congress) Pages: 26-27

O-18: Expression of Telomerase Variantand Different Cytokines in B and T Cells of Peripheral Blood of Patients with Systemic Lupus Erythematus


In this study, we tested quantitative expression of hTERT mRNA variants of T cells and B cells in lupus patients in comparison to healthy controls to find differences between these two states. We also evaluated quantitative expression of Bcl-2, CTLA-4, FoxP3, IL-4, IL-6, IL-10, IL-12, IL-17, IL-23, IFNgamma and TGF-β that contribute to alteration of immunity in lupus patients and healthy controls.