Increased Risk of Depression in Women with Polycystic Ovarian Syndrome: (A Case-Control Study) (Pages: 0-0)

Hosseini R *, Hadidi M , Rabiee M ,


Objective: PCOS is associated with several metabolic complications. Physical appearance menstrual abnormalities and difficulty conceiving are related to lower health-related quality of life scores in these patients. The aim of this study is to estimate the prevalence of depression in PCOS patients compared with controls. Materials and Methods: Women with PCOS (n=55) meeting the Rotterdam criteria for this syndrome who referred to outpatient endocrine clinic in Qom Iran compared with control subjects (n=55) who selected from healthy women and age matched from Dec.2007 to Sep.2008. Beck Depression Inventory (BDI) questionnaire was filled up for participants. Blood pressure weight height waist circumference were measured for all subjects. PCOS patients were divided in two subgroups: Depressed and non depressed. LH FSH Testosterone DHEA-S prolactin fasting plasma glucose lipid profiles were measured only in PCOS subgroups. Results: PCOS patients had significant higher prevalence of depression compared with controls (60% vs. 23.6%).The prevalence of severe depression was 21.8% vs. 1.8% in PCOS and control respectively. Systolic blood pressure (BP) diastolic BP body mass index and waist circumference were higher than controls (p