Success Rate of ICSI and its Implicating Factors in QOM Branch of Royan Institute A Retrospective 5 Year Study

Moslemi MK *, Ale Mohammad Amir A , Amiri K ,


Objective: This is a retrospective study in which we evaluated ICSI results in our scheduled couplesdefining demographic data and relating etiologic factors to the ICSI success Materials and Methods: we evaluated retrospectively ICSI results in 400 couples that underwent this procedure in a 5 year period from the beginning of 2003 to the end of 2007.the infertility causes were; male causes and femal causes or varicocelidiopathic male subfertilityazospermiaejaculation failurecervical factorendometrisistubal factor pelvic adhesionshyperprolactinemia and secondary hypogonadism.for 400 cases a total of 436 cycles of ICSI induced.for the azospermic males we used PESA or TESE for sperm retreival. Results: ICSI success per each case was 30% in our studythis rate was 27.5% per cycle.the success rate per each specific cause was as follows:ejaculation failure 33.3% azospermia; 30% male subfertility; 29.3% varicocel; 30.1% PCO; 30% tubal factor; 23.9% cervical factor; 25% pelvic adhesions; 26.7% endometriosis; 23.5% and hyperprolactinemia; 26.5%. success rate of ICSI with PESA was 27.4% this rate was 6.7% for TESEthat was significant statistically.duration of infertility in positive ICSI cases was 5.94 yearsthis rate was 7.58 years for negative cases.we have 27 twin pregnancy from 120 pregnancy(22.5%). Conclusion: ICSI is a highly demandedexpensive and nearly invasive ART technique that its use must be individualizedand each case must be carefully selected patiently.