A Review on Various Uses of N-Acetyl Cysteine

(Pages: 11-17)
Vida Mokhtari, M.Sc, 1,2,3Parvaneh Afsharian, Ph.D, 2Maryam Shahhoseini, Ph.D, 2Seyed Mehdi Kalantar, Ph.D, 1Ashraf Moini, M.D, 3,4,*
Department of Molecular Cytogenetics, Research and Clinical Center for Infertility, University of Medical Sciences, Yazd, Iran
Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
Department of Obstetrics and Gynecology, Roointan-Arash Hospital, Tehran, Iran
Department of Molecular Cytogenetics, Research and Clinical Center for Infertility, University of Medical Sciences, Yazd, Iran
Department of Genetics, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
Department of Obstetrics and Gynecology, Roointan-Arash Hospital, Tehran, Iran
* Corresponding Address: P.O.Box: 16635-148 Department of Endocrinology and Female Infertility Reproductive Biomedicine Research Center Royan Institute for Reproductive Biomedicine ACECR Tehran Iran Email:a_moini@royaninstitute.org
Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Mokhtari Vida, Afsharian Parvaneh, Shahhoseini Maryam, Kalantar Seyed Mehdi, Moini Ashraf. A Review on Various Uses of N-Acetyl Cysteine . Cell J. 2017; 19(1): 11-17.

Abstract

N-acetyl cysteine (NAC), as a nutritional supplement, is a greatly applied antioxidant in vivo and in vitro. NAC is a precursor of L-cysteine that results in glutathione elevation biosynthesis. It acts directly as a scavenger of free radicals, especially oxygen radicals. NAC is a powerful antioxidant. It is also recommended as a potential treatment option for different disorders resulted from generation of free oxygen radicals. Additionally, it is a protected and endured mucolytic drug that mellows tenacious mucous discharges. It has been used for treatment of various diseases in a direct action or in a combination with some other medications. This paper presents a review on various applications of NAC in treatment of several diseases.