Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption

(Pages: 514-527)
Massoud Seifi, D.D.S., M.S., 1Ali Arayesh, D.D.S, 2Nafise Shamloo, D.D.S., M.S., 3Roya Hamedi, D.D.S, 4,*
Department of Orthodontic, Dentofacial Deformities Research Center, Research Institute of Dental Sciences of Shahid Beheshti University of Medical Sciences, Tehran, Iran
School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Oral and Maxillofacial Pathology, Dental School of Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Orthodontic, Dentofacial Deformity Research Center, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Orthodontic, Dentofacial Deformities Research Center, Research Institute of Dental Sciences of Shahid Beheshti University of Medical Sciences, Tehran, Iran
School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Oral and Maxillofacial Pathology, Dental School of Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Orthodontic, Dentofacial Deformity Research Center, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding Address: Department of Orthodontic Dentofacial Deformity Research Center School of Dentistry Shahid Beheshti University of Medical Sciences Tehran Iran Email:dr.r.hamedi@gmail.com
Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Seifi Massoud, Arayesh Ali, Shamloo Nafise, Hamedi Roya. Effect of Nanocrystalline Hydroxyapatite Socket Preservation on Orthodontically Induced Inflammatory Root Resorption. Cell J. 2015; 16(4): 514-527.

Abstract

Objective

Orthodontically induced inflammatory root resorption (OIIRR) is considered to be an important sequel associated with orthodontic tooth movement (OTM). OTM after Socket preservation enhances the periodontal condition before orthodontic space closure. The purpose of this study is to investigate the histologic effects of NanoBone®, a new highly nonsintered porous nano-crystalline hydroxyapatite bone on root resorption following OTM.

Materials and Methods

This experimental study was conducted on four male dogs. In each dog, four defects were created at the mesial aspects of the maxillary and mandibular first premolars. The defects were filled with NanoBone®. We used the NiTi closed coil for mesial movement of the first premolar tooth. When the experimental teeth moved approximately halfway into the defects, after two months, the animals were sacrificed and we harvested the area of interest. The first premolar root and adjacent tissues were histologically evaluated. The three-way ANOVA statistical test was used for comparison.

Results

The mean root resorption in the synthetic bone substitute group was 22.87 ± 11.25×10-4mm2 in the maxilla and 21.41 ± 11.25×10-4mm2 in the mandible. Statistically, there was no significant difference compared to the control group (p>0.05).

Conclusion

The use of a substitution graft in the nano particle has some positive effects in accessing healthy periodontal tissue following orthodontic procedures without significant influence on root resorption (RR). Histological evaluation in the present study showed osteoblastic activity and remodeling environment of nanoparticles in NanoBone®.