COVID-19 and Endocrine System: A Cross-Sectional Study on 60 Patients with Endocrine Abnormality

(Pages: 182-187)
Negin Hadisi, M.Sc, 1,2Hadi Abedi, B.Sc, 2Majid Shokoohi, Ph.D, 3Seval Tasdemir, M.D, 4Shahriyar Mamikhani, M.D., 2Shahla Meshgi, M.D., 5Arian Zolfagharzadeh, M.D., 6Leila Roshangar, Ph.D., 1,*
Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Ahar Bagher-al-Olum General Hospital, Ahar, Iran
Clinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
Fertijin IVF Center Nispetiye Cad Bebek Yokusu Sokak, Etiler, Istanbul, Turkey
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Tabriz Imam Reza General Hospital, Tabriz, Iran
Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Ahar Bagher-al-Olum General Hospital, Ahar, Iran
Clinical Research Development Unit of Tabriz Valiasr Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
Fertijin IVF Center Nispetiye Cad Bebek Yokusu Sokak, Etiler, Istanbul, Turkey
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Tabriz Imam Reza General Hospital, Tabriz, Iran
*Corresponding Address: P.O.Box: 5138664393 Stem Cell Research Center Tabriz University of Medical Sciences Tabriz Iran Email:lroshangar@yahoo.com
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Hadisi Negin, Abedi Hadi, Shokoohi Majid, Tasdemir Seval, Mamikhani Shahriyar, Meshgi Shahla, Zolfagharzadeh Arian, Roshangar Leila. COVID-19 and Endocrine System: A Cross-Sectional Study on 60 Patients with Endocrine Abnormality. Cell J. 2022; 24(4): 182-187.

Abstract

Objective

COVID-19 is an infectious disease that has become pandemic with a high mortality rate. This study aims to provide new insight into the relations between SARS-CoV-2 and the Endocrine system.

Materials and Methods

In this cross-sectional study, we have hospitalized 60 patients with a positive SARA-CoV-2 PCR test. The information of complete blood count and endocrine hormones was obtained when the patients were admitted to the hospital or for a maximum of 4 days onset the hospitalization.

Results

Of 60 patients with COVID-19, forty-four (73.33%) had at least one abnormality mean item >×3. In total, 26 (43.33%), 21 (35%), 18 (30%), 13 (21.67%), 31 (51.67%), 12 (20%), 30 (50%), 25 (41.67%) patients having estradiol, follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, progesterone, testosterone, cortisol and thyroid stimulating hormone (TSH) abnormal test results, respectively. There was no change in creatinine levels. FSH has shown drastic changes in both sexes’ intensity (F: 769, P<0.0001). Although TSH had many abnormalities in women, analysis has shown no significant P value (P=0.4558). Furthermore, prolactin and testosterone mean level in men and the estradiol mean level in women have shown no significant P value (P=0.2077, P=0.1446, P=0.1351, respectively).

Conclusion

Results suggest that COVID-19 affects directly or non-directly glands and related hormones.