In Vitro Differentiation of Human Umbilical Cord Blood CD133+ Cells into Insulin Producing Cells in Co-Culture with Rat Pancreatic Mesenchymal Stem Cells

(Pages: 138-139)
Fazel Sahraneshin Samani, M.Sc, 1,2Marzieh Ebrahimi, Ph.D, 1,3,*Tahereh Zandieh, Ph.D, 1Reyhaneh Khoshchehreh, M.Sc., 1,2Mohamadreza Baghaban Eslaminejad, Ph.D., 1Nasser Aghdami, Ph.D., 3Hossein Baharvand, Ph.D., 1
Department of Stem Cells and Developmental Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
Department of Developmental Biology, University of Science and Culture, ACECR, Tehran, Iran
Department of Regenerative Biomedicine at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
Department of Stem Cells and Developmental Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
Department of Developmental Biology, University of Science and Culture, ACECR, Tehran, Iran
Department of Regenerative Biomedicine at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
- *Corresponding Address: P.O.Box: 16635-148 Department of Stem Cells and Developmental Biology at Cell Science Research Center Royan Institute for Stem Cell Biology and Technology ACECR Tehran Iran Email:mebrahimi@royaninstitute.org
Any use, distribution, reproduction or abstract of this publication in any medium, with the exception of commercial purposes, is permitted provided the original work is properly cited This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Sahraneshin Samani Fazel, Ebrahimi Marzieh, Zandieh Tahereh, Khoshchehreh Reyhaneh, Baghaban Eslaminejad Mohamadreza, Aghdami Nasser, Baharvand Hossein. In Vitro Differentiation of Human Umbilical Cord Blood CD133+ Cells into Insulin Producing Cells in Co-Culture with Rat Pancreatic Mesenchymal Stem Cells. Cell J. 2021; 23(1): 138-139.

Abstract

In this article which was published in Cell J, Vol 17, No 2, Summer 2015, on pages 211-220, the authors found that Figures 3 and 4 had some errors that accidentally happened during organizing figures as well as because of mislabeling of some images and saving them in an incorrect folder. The following figures are corrected.

The authors would like to apologies for any inconvenience caused.

- Immunofluorescence staining for insulin (FITC) and C-peptide (FITC) in differentiation umbilical cord blood cluster of differentiation 133+ (UCBCD133+) cells. A. The bright field images of pre- and post-differentiation UCB-CD133+ cells. Expressions of insulin and C-peptide conjugate with FITC (green) and nucleus stained with DAPI and B. Bright field images of mesenchymal stem cells (MSCs) pre- and postdifferentiation and lack of expressions of insulin and C-peptide in the cells (×100).
- Effect of rat pancreatic mesenchymal cells on differentiation of umbilical cord blood cluster of differentiation (UCB-CD133+) into pancreatic β cells. Morphology and immunophenotyping of cells pre- and post-differentiation (×100). Immunofluorescence staining of cells for insulin (FITC) and C-peptide (FITC) in the groups co-cultured with rat pancreatic stromal cells. As observed with fluorescent microscope,insulin and C-peptide expressed after pancreatic differentiation in islet-like clusters. Human cadaver pancreas was the positive control. Nuclei were counterstained with 4΄,6-diamidino-2- phenylindole (DAPI).